If you’re new to cannabis, you may not know about THCCBD, and terpenes, but they’re an integral part to the cannabis plant that all novice and expert consumers should know aboutEven if you’re just entering the cannabis world, it’s likely you’ve heard about various ratios. But the real question is: why do so many cannabis enthusiasts care about ratios? Answer: different cannabinoids (THC, CBD, THCa, etc.) work in tandem when consumed—a process known as the entourage effect. The cannabis Entourage Effect is the idea that various compounds found in the cannabis plant act in synergy together to create enhanced therapeutic effects, and that they work better in tandem than they do on their own. 

What is the Entourage Effect? 

The Entourage Effect is the idea that molecules that occur together in nature will interact in useful ways. With cannabis, this means that the benefit of capturing the whole plant has higher therapeutic value than just consuming isolated cannabinoids. Cannabis has a lot of amazing compounds such as terpenes, cannabinoids, cannabinoid acids, as well as phytonutrients. These molecular compounds are also naturally found in other plants and insects. Terpenes are just one aspect of the cannabis plant: the natural oils which are accompanied by a distinct aroma and viscosity. Terpenes and cannabinoids (such as CBD and THC) work together to maximize benefits in the body. Lab and patient-based studies reveal that while CBD or THC can work well independently, they can often create better outcomes in when taken in combination.  

Entourage Effect with CBD & THC 

When you choose a specific ratio, especially with naturally occurring terpenes, they have the potential to cause even better results. The Entourage Effect is one of the leading theories influencing cannabis research worldwide. It has been shown that terpenes, for example, not only allow cannabinoids to pass through the bloodstream and into the body’s cannabinoid receptors more easily, but they can also work against the memory loss caused by THC and help you relax and relieve stress. This is what the Entourage Effect is all about! The way CBD and THC works together is why our products help you feel better. Just like a great teammate, these two cannabinoids help each other be their best selves! It should be noted that everyone’s body is different, so a 1:3 CBD:THC ratio might help your friend sleep well, but it might give you a little more than you bargained for. In that case, a 3:1 CBD:THC ratio or a 30:1 CBD:THC ratio might be a better option for you because the CBD counterbalances the intoxicating effect of the THC, providing you with the restful sleep you’re looking for.  

The Endocannabinoid System & Entourage Effect 

The endogenous cannabinoid system, also known as the endocannabinoid system (ECS), can be thought of as the air traffic control center for the body. It controls physiological processes including appetite, pain sensation, mood, and memory.  The ECS consists of two primary cannabinoid receptors: CB1 receptors (most concentrated in the central nervous system and brain) and CB2 receptors (abundant in the cardiovascular, gastrointestinal, and peripheral nervous systems). The natural cannabinoids and phytonutrients found in cannabis communicate with these signal receptors of the ECS to help reduce minor aches, acute discomfort, and normal inflammation 

Cannabinoids and naturally-occurring endocannabinoids affect us by binding with the CB1 and CB2 receptors found throughout our bodies, much like a system of locks and keys. If you think of cannabinoids such as THC, CBD, or CBN as the keys, then the CB1 & CB2 receptors are the corresponding locks that they fit into. These interactions are what drive modern research into cannabinoids and will lead to future medical discoveries as research on the cannabis plant continues to grow. The physiological effects of cannabinoids vary depending on the location of the cannabinoid receptors that they stimulate. These receptors are common in our limbic system (the part of the brain that affects memory, cognition, and psychomotor performance) our mesolimbic pathway (associated with feelings of reward), and are also widely distributed in areas governing discomfort perception. Products that capture the whole essence of the plant and provide a full spectrum of the plant’s cannabinoids and natural terpene profile interact on a larger scale with our endocannabinoid system. 

Whole Plant Full Spectrum™ Products 

Papa & Barkley is committed to creating wellness products that adhere to the highest quality standards. It is our firm belief that cannabis is an individualized medicine. Different bodies with varying health concerns require different ratios of cannabinoids. We believe that optimal therapeutic efficacy requires the use of both CBD, the non-intoxicating compound, and THC.  

Each person’s body and endocannabinoid system is unique, with different needs and receptors. We believe that cannabis is not one-size-fits-all. We also believe—thanks to research—that optimal therapeutic efficacy requires the use of both CBD, the non-intoxicating compound in cannabis, and THC, its intoxicating component. Papa & Barkley offers a suite of products in different ratios, allowing you to select the best ratio for your therapeutic needs. 

At Papa & Barkley, we’re known for our award-winning Releaf Balm, but we’re so much more than that. The creation of our balm allowed us to branch out and create Whole Plant Full Spectrum™ cannabis wellness products that help you feel better every day. Sore muscles and joints? Try our Releaf Balm or Body Oil – the whole plant and soothing essential oils are great for post-workout recoveryNeed to relax and get a better night’s rest? We have myriad ratio options of tinctures and capsules to help you sleep tight. Want to make your hike even better? Grab a gummy and hit the trail! No matter what kind of relief you’re looking for, we’re here to help you feel better every day. 

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Cannabis Entourage Effect
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Cannabis Entourage Effect
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You know about THC, CBD, and Terpenes… but why do so many cannabis enthusiasts care about their ratios to each other? This is because these different cannabinoids work in tandem
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papa & barkley
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