CBD & THC: What’s the Right Dose?

CBD & THC: What’s the Right Dose?

What is the right dose of THC or CBD to take?

Why do milligrams matter?

Often when it comes to cannabis dosing, and especially with orally consumed products like tinctures and edibles, cannabinoid content is measured in milligrams. Milligram counts are the cornerstone of proper dosing, especially with ingested products like tinctures and capsules, so understanding them is key to maximizing their effects. For the new user this can be a bit confusing at first, so we’re going to break it down and make it easy for you to know exactly how to fit your dosage needs. The common threshold for feeling the effects of THC is 2MG for most new users, depending on their weight. At around 2.5MG, most people feel a high similar in intensity to a glass of wine or beer. At around 5-10 MG, the most significant effects are felt by infrequent users, and can provide strong psychoactivity.

How Much THC Edibles Should I Take?

When dosing, especially if it’s your first time, it’s important to take things slowly so that you don’t reach an uncomfortable level. With edibles, just take 2.5 milligrams at a time, waiting 45 to 90 minutes in between doses, until your desired level of relief is achieved.

Edibles tend to metabolize THC into a form that is twice as strong and longer lasting, so it’s important to take your time and really figure out what works for you.

Be careful when dosing with THC edibles to maximize effects
The right amount when dosing with cannabis by smoking is different for everyone

How Much Cannabis Should I Smoke?

When it comes to smoking, it becomes a bit more difficult to measure proper dosing, as strains vary. The best rule of thumb for smoking is to start with flowers, as opposed to strong concentrates, and take it one inhalation at a time.

Milligram counts are essential to proper dosing, so it’s a good idea to always buy products that provide third party testing. Third party testing adds legitimacy to the cannabis industry by ensuring that all labels are accurate and that the contents of a product are always consistent.

How Much CBD or THC Tincture Should I Take?


Tinctures, when applied under the tongue and absorbed through the mouth, absorb much faster into your bloodstream and avoid the relatively high wait time of digested edibles.

Additionally, tinctures are odorless and not easily confusable with normal food items. Excellent for medicinal consumption, tinctures can come rich in CBD and THCa, both non-psychoactive but extremely beneficial, and avoid the irritation and detriments from combustion or inhalation.

To properly use a tincture, you’re going to want to place one drop at a time under the tongue, and wait about 30 seconds before swallowing, allowing the tincture time to absorb into the mouth lining. Wait 15 minutes in between drops to figure out your desired dosage, which you’ll be able to take all at once in the future. Tinctures can also be applied to food, but like edibles, this will take longer to digest and to take effect.

Each person's ratios are different when dosing with CBD & THC tinctures

How Much Should I Dose With THC? With CBD?


Proper dosage is especially important with cannabis products, as cannabinoids do not increase in therapeutic effects with a higher dosage like most medications do. While cannabis is extremely safe to use, dosage is key in extracting the greatest positive effects and avoiding adverse effects like an uncomfortable level of psychoactivity or desensitization to cannabinoids.

With cannabis, less is more when unlocking its benefits. Among the easiest ways to properly dose cannabis is the use of tinctures. These are concentrated cannabis flower extract dissolved in alcohol. Not only are tinctures far lower in calories than traditional edibles, they also come in several variations, both psychoactive and non, making it easy to find one for your needs. Average strength is about 30mg per milliliter but can also vary from product to product.

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THC & Topicals

THC & Topicals

THC & Topicals

With Mitch Earleywine, Ph.D.

You’ve heard of CBD but you may be asking: why is there THC in my topical?

As Mitch Earleywine Ph.D. puts it, “research reveals that cannabinoids can help pain and inflammation. Generally, THC might have the edge for most types of pain while CBD may be better for some kinds of inflammation.” Data reveal that both THC and CBD have both analgesic and anti-inflammatory properties. Nevertheless, THC is likely the better analgesic and CBD likely the better anti-inflammatory. Evidence for CBD’s anti-inflammatory effects is reviewed here. A stellar review of cannabinoids’ impact on inflammation is here. Relevant to arthritis, this animal study shows the effects of CBD for both inflammation and pain.

Cannabis Entourage Effect

The entourage effect likely applies for topicals as well, meaning that different types of cannabinoids and terpenes working together is ideal. However, relevant data is not published yet. We do get terpene absorption from a topical, but the research is behind the curve for which terpenes penetrate best.

Will THC Topicals Get Me High?

It’s possible that a low-tolerance or inexperienced user could notice subjective effects of a local, topical application above 15mg THC, but most of these are pleasant and non-impairing. In addition, the other active ingredients have delightful “aromatherapy” effects, so application near the nose is bound to create some relaxation or cognitive enhancement. (Our own peppermint-containing products have the potential to perk folks up and even improve clerical tasks.)

CBD & THC Medical Research

We can confirm transdermal absorption for both THC and CBD, as well as the anti-inflammatory and analgesic effects for both, but no one has pitted them against each other in humans in a transdermal experiment. Two of the seminal studies of transdermal THC are referenced below; they emphasize it really depends on the carrier—the other substances in the balm or patch. Our products have multiple substances that contribute to analgesia and anti-inflammatory properties. In addition, our other components (peppermint, in particular) also contribute, as mentioned above.

What is THC?

What is THC?

THC is also an active ingredient in cannabis and is arguably the most famous cannabinoid associated with recreational use. However, here at Papa & Barkley, we focus on the wellness aspects of the plant and THC is an awesome acute pain manager.

THC comes in a variety of versions. THCa, which can be used to manage paid with limited psychoactive effects similar to Advil. However, Delta-9-THC has awesome pain management power that rivals opiates, but with improper dosing can have cognitive effects.


What is Tetrahydrocannabinol (THC)?


The main ingredient in cannabis is delta-9-tetrahydrocannabinol (THC). The properties of THC were first described in the 1940’s, but our understanding of THC has dramatically improved in the last six decades. THC is an activator of the cannabinoid 1 (CB1) receptor in our bodies. on of the brain during THC intoxication. THC can affect numerous functions in the body to varying degrees depending on the person.

Medical Uses For THC


THC, or tetrahydrocannabinol, is the chemical responsible for most of the psychological effects that are commonly known and experienced. It acts in a similar fashion as the cannabinoids made naturally by the body. Cannabinoid receptors are concentrated in certain areas of the brain associated with thinking, memory, pleasure, and coordination. THC attaches to these receptors in the body to help with pain and inflammation. There are documented cases of THC helping cancer patients and others with medical ailments find relief from their symptoms. 

What is THCa?

What is THCa?

You’ve heard of THC, the psychoactive compound in cannabis, but did you know that it actually doesn’t exist in the raw plant?

What is THCa?

 THCa (tetrahydrocannabinolic acid) is the non-psychoactive acid form of THC found in the plant when raw. THC starts off as THC-A, which becomes THC when the plant is heated, burned, or vaporized, a process known as decarboxylation. While THC gives you that familiar “high”, THC-A is actually non psychoactive, which is why eating a cannabis flower fresh off the plant won’t give you a psychoactive effect.

What are the benefits of THCa?


Emerging research is beginning to show the potential benefits derived from THCa without the high.

These include fighting nausea and appetite loss, anti-inflammatory applications, pain relief, and as a neuro-protective agent. THC-A truly is proving to be a non-psychoactive alternative to many of the benefits of THC, and further research will only open the door to more possibilities.

THC-A products and even juiced raw plants are becoming more and more available as demand grows. THCa products need to be kept in a cool, dark place… as heat will transform the volatile molecule into psychoactive THC. They’re great for direct oral and sublingual delivery, and can even be added to cold drinks like fresh juice or a smoothie.

Cannabinoids For Health & Wellness


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How to Find the Right CBD to THC Ratio

How to Find the Right CBD to THC Ratio

Right Ratio CBD to THC

Have you ever seen numbers like 1:3, 3:1, and 1:30 on your favorite product? Here’s why: these numbers represent the ratio of CBD to THC. Understanding ratios and how to apply them is an important step in figuring out which product or strain is right for you.

High THC Dosing Ratio

A high THC ratio with little or no CBD can be very psychoactive and provide a powerful elevated effect. A topical application, however, will not result in a high. These ratios are preferred primarily by recreational users, although it can also be used to help with anxiety, mood improvement, and help with nausea & vomiting.

Topically, THC can also help manage acute pain. Balanced ratios are the most popular variety because they have the widest range of uses. These even blends are helpful for both physical healing and relaxation and for achieving the psychoactive properties and benefits of THC.

In fact, any ratios that include both THC and CBD, even in small amounts, activate the entourage effect and are of the greatest overall value compared to pure THC and CBD mixtures.

knowing the right THC and CBD ratios will help you with accurate dosing

High CBD Dosing Ratio

Low to no THC and high CBD mixtures, as well as mixtures that include THC-A will provide the relief and swelling reduction without much psychoactivity, if any. These ratios are of most use to those who wish to use cannabis medicinally and for pain relief, relaxation, and wellness without psychoactive effects.

Understanding the dosing ratios associated with THC and CBD can help you refine your cannabis experience and tailor it to your needs.